The measurement of folic acid activity in serum: a diagnostic aid in the differentiation of the megaloblastic anemias.
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چکیده
منابع مشابه
Differentiation between vitamin B 12-deficient and folic acid-deficient megaloblastic anemias with C14-histidine.
.‘ 4EGALOBLASTIC ANEMIAS result from a relative or absolute defiI VI ciency of vitamin B12 or folic acid. Often it is difficult to make this etiologic differentiation, either from clinical observations or by use of routine hematologic procedures. Several methods which have been devised to evaluate folic acid deficiency have been reviewed recently.’ These include: therapeutic trial of “physiolog...
متن کاملDiagnostic Value of Small Oral Doses of Folic Acid in Megaloblastic Anaemia.
The introduction of reliable techniques for the measurement of serum levels of vitamin B12 and folate has meant that megaloblastic anaemias can be more readily classified as being due to deficiency of one or occasionally both of these substances. The excretion of formiminoglutamic acid (figlu) in the urine of patients with folic-acid deficiency has further aided this differentiation. However, u...
متن کاملPyrexia in a Patient with Megaloblastic Anemia: A Case Report and Literature Review
Deficiency of vitamin B12 and/or folic acid as a cause of pyrexia, though known, is rarely reported in literature. We aimed to report a case in a 51 year old woman, who presented with fever and pancytopenia and was diagnosed to have megaloblastic anemia secondary to vitamin B12 and folate deficiency. The pyrexia subsided following the intramuscular injection of vitamin B12 and oral folic acid a...
متن کاملMegaloblastic Anemia in Pregnancy
MegalobJastic Anemia in Pregnancy Megaloblastic Anemia is one of The Rather Common Diseases of Pregnant Women Caused by Folic acid Deficiency The Disease Might Be Hazardous To affected Mothers and also Could be Fatal for foetus too. Megaloblastic Pregnant Women Will have Signs and Symptoms of This Disease mostly after 29th. Week of pregnancy. Adequate amount of Folate Will prevent Compli...
متن کاملInterrelations of vitamin B12 and folic acid metabolism: folic acid clearance studies.
The studies of many investigators have led to a unified concept of the megaloblastic anemias as a single morphologic entity due to defective nucleoprotein synthesis from various causes. The vast majority of patients with megaloblastic anemia have been found to have deficiency of vitamin B12, of folic acid, or of both vitamins. For this reason, the possible interrelations of these two vitamins h...
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ورودعنوان ژورنال:
- Blood
دوره 15 شماره
صفحات -
تاریخ انتشار 1960